Packages containing 30 extended-release coated tablets.
Controlled release coated tablets, 12.5 and 25 mg: Packs containing 30 controlled release coated tablets.
Containers with 30 long-acting coated tablets.
ROSTRUM 25: packs containing 10 and 30 coated tablets.
ROSTRUM 100: packs containing 30 coated tablets.
ROSTRUM 200: packs containing 30 coated tablets.
Composition: VALCAS 250 - Each coated tablet contains: sodium divalproate (equivalent to 250 mg of valproic acid) 269.10 mg. Excipients q.s. VALCAS 500 - Each coated tablet contains: sodium divalproate (equivalent to 500 mg of valproic acid) 538.20 mg. Excipients: q.s.
Therapeutic action: anticonvulsant. Treatment of bipolar disorder. Migraine prophylaxis.
Indications: Epilepsy: VALCAS is indicated as a monotherapy and in combination for patients with partial and complex crisis that occur in isolation or associated with other type of crisis.
VALCAS is also indicated as a monotherapy or in combination in the treatment of patients with simple and complex absence crisis, and as an adjuvant in patients with multiple crisis that include absence.
Mania: VALCAS is indicated for the treatment of maniac episodes associated with bipolar disorder.
Migraine: VALCAS is indicated for the prophylaxis of migraines.
Valproic acid may be harmful for the fetus; therefore, the use of VALCAS should be considered in women of childbearing potential only after a thorough discussion about this risk with the patient and after assessing its use against the potential drug benefits.
Dosage: Epilepsy: initially, 10-15 mg/kg/day. Up to 60 mg/kg/day. Mania: initially, 750 mg/day (split dose). Maximum recommended dose: 60 mg/kg/day. Migraine: initially, 500 mg/day (divided in two doses). Up to 1 g/day.
Contraindications: liver disease or significant hepatic impairments, patients with known urea cycle disorders, hypersensitivity to the drug or to any of the Medicinal Specialty components.
Hoy supplied: packages containing 50 coated tablets.